When CBD recently hit the market in the medicinal drugs space, there were numerous speculations about how potent it really is. Researchers, biochemists, scientists, healthcare professionals, and pharmaceutical companies were also concerned about whether CBD is safe for continued use or not. However, over the past decade, it has proven to be a powerful agent in dealing with numerous medical conditions and their symptoms.
From several types of cancer to seizures and epilepsy to dementia, CBD has shown great potential in easing the lives of patients. Pain Relief Sprays, Pain Relief Roll-Ons, and Pain Relief Creams have helped people ease out pain and inflammation on their skin, bones, and other organs. Facial Serums, Face Creams, Anti Aging Facial Serums, Glow Oils, and Sleeping Masks with CBD as a major constituent has helped people get healthy and young skin by treating skin conditions like fungal infections, wounds, eczema, psoriasis, severe acne, and more.
CBD’s great performance in treating skin conditions led to further research and development in this area. After several years, CBD has now also been shown to be very effective in reducing inflammation in human sebocytes. This effectiveness can be very beneficial in helping deal with severe acne and oil secretion in humans. What exactly are human sebocytes, and how does CBD help in reducing inflammation in them? Let’s have a closer, detailed look at the same.
What are human sebocytes?
Before we talk about what human sebocytes are, let’s first focus on the gland that these sebocytes cells constitute. This gland is called the sebaceous gland. It is an exocrine gland (the secretions are directly released into the epithelium instead of the human bloodstream) that opens up into a hair follicle. Sebocytes are cells that make up these sebaceous glands in the human body.
Sebaceous glands are largely present on the face, scalp, and in reduced numbers in other parts of the body. However, they are not found on your palms and soles. These glands secrete matter that’s oily or waxy. These oily secretions are highly useful in creating lubrication on the skin. This lubrication helps keep your eyes moist, your nipples lubricated, and scalp slightly oily to prevent rashes, cracks, blisters, or drying out.
This oily secretion is released when the sebocyte membrane in the sebaceous glands rupture. Now, the release of this oily waxy secretion is very beneficial for humans in general. However, problems arise when there’s an issue with the sebocytes. Overstimulation or inflammation of these human sebocytes can cause the sebaceous glands to produce a lot of oil and make the skin and scalp red, irritated, and highly inflamed.
What happens when sebocytes behave abnormally?
When your skin produces more sebum that is required, you risk the chance of clogging your pores. Usually, your pores can get clogged by pollutants or makeup and cause whiteheads or blackheads. These can be easily remedied by over-the-counter medications and using a good face wash regularly. However, if your pores get clogged very regularly due to extra sebum secretion or dead skin, it can result in very severe acne. Sebum and dead skin need to be constantly removed from your skin to keep it clean and healthy. Accumulation of these can clog pores making it very difficult to clean them out with regular medications.
Your skin isn’t the only place on your body that can get severely affected by extra sebum production. If the same happens in your scalp, your scalp can get very oily. While this is manageable under normal conditions, severe cases need a little more than just regular shampooing with an appropriate cleanser. If this problem isn’t addressed, it can cause your scalp to become incredibly itchy and inflamed. In severe cases, people even start to lose their hair, mostly in patterns.
The most common skin disorders arising from the inflammation of human sebocytes are sebaceous hyperplasia, sebaceous adenoma, and severe acne. There are several reasons for human sebocytes to behave abnormally. Some of them include skin damage by exposure to UV rays, pollution, and an unhealthy diet. There are several products in the market that can help you deal with inflammation in human sebocytes. Amongst the many available, CBD-based products such as Facial Serums, Face Creams, Anti Aging Facial Serums, Glow Oils, and Sleeping Masks have proven to be immensely useful.
How is CBD effective in reducing inflammation in human sebocytes?
Numerous physiological processes in our body are regulated by the endocannabinoid system. The secretion of sebum from sebaceous glands is one such process. Due to the lipogenic actions of various compounds, sebocytes sometimes become overstimulated or inflamed, causing an oversecretion of sebum. This, in turn, causes severe skin and scalp conditions that are highly problematic and uncomfortable for the patient.
Now, CBD is a substance that can affect the way your body’s endocannabinoid system works. It combines with the CB1 and CB2 receptors in the endocannabinoid system to change how physiological processes take place in our bodies. When someone suffering from inflammation of the human sebocytes takes a CBD-based product to treat the condition, the endocannabinoid system gets affected to bring about the desired results. In a 2014 study published in the Journal of Clinical Investigation, it was found that CBD showed both anti-inflammatory and sebostatic effects on human sebocytes.
In this study, when a culture of human sebocytes was treated with CBD, the lipogenic actions were inhibited. Due to this inhibition, human sebocytes then do not get overstimulated or inflamed, causing severe skin problems like acute acne. CBD also activates TRPV4, which prevents the genesis of sebocytes by inhibiting the pathway that leads to its genesis. The great thing about this study was that not only did they prove that CBD has sebostatic properties but also anti-inflammatory properties.
Moreover, CBD can even prevent any other problems that arise as a result of acne. When a person’s scalp or skin is severely inflamed due to abnormally behaving sebocytes, they also become highly susceptible to several other bacterial and fungal infections. Itching, redness, burning sensation, and inflammation become very prevalent in such patients. Treating such cases with traditional drugs can get very tough since the host of medicines might interact with each other, thus limiting their positive effects. This can be taken care of with CBD.
A 2016 review published in Plant Science showed that CBD has a high potential in treating fungal and bacterial infections of both the skin and the scalp. This thoroughly increases the effectiveness of CBD since it acts like multipurpose skincare and therapy product. Plus, due to the lightening effects that CBD carries, it is also highly effective in dealing with scarring and dark pigmentation that may arise from skin conditions. Now that we are aware of how CBD can reduce inflammation in human sebocytes, let us have a look at how patients can use this product to get the desired results.
Treating inflammation in human sebocytes with CBD
When it comes to skin and scalp inflammation, it is important to treat the condition gently without any harsh drugs. If any harsh drugs are used, the surrounding skin can get severely affected, causing even more problems than before. Plus, the problem area itself can develop side effects if the drugs used aren’t gentle on the skin. To avoid such complications for the patient, it is crucial to use something that’s both gentle and therapeutic. This is where CBD comes into play.
CBD-based products are highly effective in preventing the activation of cytokines. It is these cytokines that initiate inflammation in the human body. Moreover, owing to their sebostatic properties, CBD is highly effective in treating the root cause of the problem and preventing the sebocytes from getting inflamed. The good thing about CBD is that it comes in various forms - pills, capsules, oils, tinctures, and more. Because of this, a patient can use CBD in the form that they find most comfortable. Since skin conditions are highly uncomfortable, some people do not like putting the creams or oils directly on the problem area. For them, taking pills is much better. It is this same flexibility that CBD products offer.
Here are the different ways in which CBD-based products can be used to reduce inflammation in human sebocytes.
Pills and Capsules
Several pharmaceutical companies manufacture CBD-based pills and capsules. These pills and capsules have CBD oil in them at a particular concentration that’s best-suited for the problem to be treated. Patients suffering from inflamed sebocytes can try CBD pills and capsules to treat the condition. Since they are easily ingestible, patients can simply pop one and not worry about having to apply it directly to the problem area.
This is very suitable for those who find it extremely uncomfortable to apply medicines directly on their skin. It is also more suited for people whose condition isn’t very serious. In cases where the inflammation is too severe, topicals are found to be more readily effective. Do remember to consult your doctor before starting any medications.
Facial Serums, Face Creams, Body Oils, and Recovery Lotions
There are numerous Facial Serums, Face Creams, Body Oils, and Recovery Lotions available in the market that can be used to deal with inflammation of the sebocytes. These are infused with CBD oil and are highly potent and effective in bringing down the inflammation. Moreover, the great thing about these topicals is that CBD-based Body Oils can even be applied on the scalp if that’s the area you are trying to treat. Using a few drops of the oil continually or as instructed by your doctor is enough to see good results. Thus, it’s not just effective for your skin but also the scalp.
The most important advantage of using these topicals is that it is more effective than pills and capsules. They have higher bioavailability, which means that it gets more readily absorbed in your body and affects the target area more powerfully. Thus, using these Facial Serums, Face Creams, Body Oils, and Recovery Lotions can bring about faster results than pills and capsules. However, it is very important to note that self-medicating is not recommended when it comes to CBD products. Like any other drug, it is important for you to consult your doctor and get a prescription before you use these Facial Serums, Face Creams, Body Oils, and Recovery Lotions to treat the inflammation.
Edibles and Tinctures
In some cases, giving the patient edibles or tinctures can be a good mode as well. Edibles such as CBD infused gummy bears, chocolates, or candies can be used. They are easy to chew and ingest and are suitable for people who cannot take pills and capsules comfortably. One can also use tinctures where a few drops of the oil are put under the patient’s tongue. The area under the tongue has a high absorption value and helps the CBD reach the target problem area faster and in higher quantities. These are great options for mild cases where topicals are not necessary. Other than these, intramucosal and oromucosal CBD products are also available in almost all drug stores.
Inflammation of human sebocytes can result in very problematic and long-term skin conditions. They make the patient incredibly uncomfortable, and living life with ease becomes difficult day after day. Moreover, the discomfort can cause patients to become highly irritable as well. CBD drugs can work as a therapeutic gateway for those patients who aren’t able to find relief from traditional drugs. Their high bioavailability and direct effect on the root cause makes it a powerful agent to deal with this inflammation.
Highly effective and suitable for sensitive skin, CBD has minimal side effects. Other than this, we also recommend adding healthy food items in your diet and eliminating junk food that can trigger excessive sebum production. In our modern lives, where bad diet and pollution can wreak havoc on our skin, taking such precautions is crucial. Wash your face regularly, use CBD-based Facial Serums, Face Creams, Body Oils, and Recovery Lotions, and live a comfortable life without dealing with inflammation of the human sebocytes.